After alum injection, platelet aggregation was significantly lowered. Padikaram (alum)a unique drug and its utilization in Siddha medicine: a pharmacological review. New York: Springer Publishing Company, 1974., p. 11. Of the compounds tested, only desferrioxamine and ethylenediamine-N,N'-bis(2-dihydroxyphenylacetic acid) increased urinary output, 4 and 2.6 times, respectively, of aluminum when compared to the control. Drinking Water Before Bed Is It A Good Idea? -Cosmetic or drug astringent, helping the shrinkage of tissues and the dry of secretions11 Hence, you should consult a doctor before taking alum and disclose to your doctor if you take any other medicine or supplement. 2020; 9 (2): 1-3. /Aluminum salts/, Booth, N.H., L.E. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. If you believe you are experiencing an interaction, contact a healthcare provider immediately. It is obtained from the soil ore found in Nepal, Bihar, Punjab, and the Kathiawar area.1 It is a colourless, clear, odourless, crystalline mass or granular powder with a sweetish astringent flavour. 2019;14(2):1-2. Avoid life-threatening adverse drug events & improve clinical decision support. There was no significant correlation between the two estimations in any tissue measured. Shibe Yamani (Alum) And Its Therapeutic Effects In Unani System of Medicine:A Review. Vols I, II. (1997). Available from: Masuma Zaki, Lubna Fatima, Wajeeha Begum. Five patients with malignant hemopathies, including four treated by bone marrow transplantation, developed cyclophosphamide induced hemorrhagic cystitis that failed to respond to the usual treatments. Blood aluminum concn of control subjects did not show significant differences when compared with data reported by other authors. PharmEasy's health blog section is an extension of the online aggregator business. /Aluminum cmpd/, Friberg, L., Nordberg, G.F., Kessler, E. and Vouk, V.B. In vitro tests used two concentrations of each chelator with a zero concentration control and each chelator was tested 3 times for solubilization. THEY HAVE ALSO BEEN USED IN MGMNT OF FUNGAL INFECTIONS & ECZEMATOID DERMATITIS. Urine aluminum:creatinine ratios (ug:mg) became elevated and significantly higher in the high aluminum group (1.6 + or - 0.38 vs 0.5 + or - 0.1) at the third sampling point (mean 19 days). Brain 2-Thiobarbituric acid reactive substances production in the presence and absence of iron was similar between the 100 and 500 aluminum groups. The additional of ferrous iron increased 2-thiobarbituric acid reactive substances production in-brain homogenates from all 3 dietary group. /ALUMINUM/, Browning, E. Toxicity of Industrial Metals. (4) Douches: ammonium aluminum sulfate (5- 16%); potassium aluminum sulfate; and alum (12%). (ed.). Also Read: Kalijiri: Uses, Benefits, Side Effects & More! Potassium alum may increase the hyperkalemic activities of Amiodarone. (2) Internal analgesics (buffered aspirins): aluminum hydroxide and aluminum glycinate. No local side effects were recorded, but one patient had a single seizure. AHFS Drug information 90.. Bethesda. In an animal model, the antiplatelet action of alum was investigated in terms of platelet aggregation and bleeding time. : Amsterdam: Elsevier Science Publishers B.V., 1986., p. 8, ABSORPTION & REMOVAL OF INJECTED ALUMINUM COMPOUNDS SUCH AS ALUMINUM HYDROXIDE FROM IM SITES & FROM PERITONEAL CAVITY IS SLOW BUT IT IS COMPLETE IN A FEW DAYS, PROVIDED THE DOSES ARE WITHIN PHYSIOLOGIC LIMITS & NOT MIXED WITH ANY IRRITANTS SUCH AS ANIONS OF CHLORIDE & NITRATE. On this health blog, you will find articles on lifestyle with topics on food, myth breakers, home remedies, health tips, etc. In short, the PharmEasy health blog is the go-to destination for all healthcare requirements. : Amsterdam: Elsevier Science Publishers B.V., 1986., p. 7, Studies strongly suggest that aluminum in the gastrointestinal tract and its subsequent distribution in tissue can be influenced by increasing the concentration of parathyroid hormone. The iron induced 2-thiobarbituric acid reactive substances production was 26% higher in the 1000 aluminum brain homogenates than in the 100 aluminum group (4.9 vs. 3.9 nmol 2-thiobarbituric acid reactive subtances/mg protein). CABARDO AM JR; PERIODONTAL POWDER. /Aluminum/, Glick JL; Med Hypotheses 31 (3): 211-25 (1990), Aluminum is established as a neurotoxin, although the basis for its toxicity is unknown. Workers exposed to aluminum in connection with the production of raw aluminum, aluminum sulfate, corundum or welding of aluminum have elevated levels of aluminum in urine. /ALUMINUM CMPD, Venugopal, B. and T.D. [, Berlyne GM, Ben-Ari J, Pest D, Weinberger J, Stern M, Levine R, Gilmore GR: Hyperaluminaemia from aluminum resins in renal failure. Potassium alum is an active ingredient in baking powder.1. It may be made suitable for potential health uses.2 It is found in many pharmaceutical, cosmetic, and food products. Medical toxicology: diagnosis and treatment of human poisoning. 5th ed. The absence of an interaction does not necessarily mean no interactions exist. These results suggest that raised tissue aluminum concentrations reported in Alzheimer's disease are not an exaggeration of normal aging proces, are not likely to be simply secondary to increased dietray aluminum intake, and that Alzheimer's disease does not represent the chronic toxic effect of moderately raised aluminum levels at the upper end of the normal distribution. Alum might show some effect on post-operative wounds.Alum may be dissolvedin water and used for helping with the post-operative wounds.1 There is a need for more studies to prove its effectiveness for post-operative wounds. Drinking water and health (4th ed.). The reduced clearance of aluminum compounds is due to the high protein binding.3, There is no evidence of potassium alum that demonstrates any suspicious for it to be a hazard for the consumers in the currently approved levels of use.9, Drug created at September 15, 2015 20:19 / Updated at January 02, 2022 12:00. National academy press. Tissue aluminum concentrations were measured in 14 patients after 7 days of dietary control and repeated approximeately 6 weeks later, again after 7 days of dietary control. It is also found in cosmetics and deodorants. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 1010, Medicinally, aluminum and its salts are used in antacids, antidiarrheals, and protective dermatological pastes. [, Kovalchik MT, Kaehny WD, Hegg AP, Jackson JT, Alfrey AC: Aluminum kinetics during hemodialysis. White is known as phitkari, green is known as heera kasees, yellow is known as kasees, and red is known as surkh phitkari. You must consult a qualified doctor before taking any herbal supplements. Available from: Wen Y, Shi Y. Alum: an old dog with new tricks. Therefore, kindly consult a doctor. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1990 (Plus Supplements 1990)., p. 1618, Cations that form insoluble phosphates interfere with the absorption of phosphorus. OCCASIONALLY USED FOR STOMATITIS & VAGINAL & INTRAUTERINE THERAPY IN CATTLE. 2nd ed. (ed.). Metal Toxicity in Mammals, 2. Stronger solutions (5 to 10%) harden the epidermis and are useful in treating soft corns or sore feet; alum in purified talc has been used as a foot powder. Handbook of the Toxicology of Metals. MEDICATION (VET): TOPICALLY, IN ASTRINGENT WASHES, POWDERS, & "LEG TIGHTENERS" FOR HORSES. Vignesh K, Niresh SJ, Saravanasingh K, Uma AP. The most notable quality alum, according to Unani physicians, is one that easily shatters.3, Various properties of alum are listed below.3. IN TREATMENT OF GUM BLEEDING & CHRONIC & ACUTE GINGIVITIS. This is evidence of pulmonary absorption. Therefore, do not self-medicate. Lancet. This blog also features expert articles on health by health and fitness experts, doctors, celebrities, dieticians and much more. In 1977, a positive correlation between increased serum parathyroid hormone and serum aluminum levels in dialysis patients had been reported. Aluminium(3+) Ion Potassium Disulfate, 38. Not all assays were done on all subjects (eg, serum aluminum on 76 subjects, whole blood aluminum on 42 subjects), but tissue aluminum concentrations were estimated on more than one occasion on 32 subjects. contain bacterial antigens. 11th ed. The oral intake of potash alum might help in reduction of body weight, food intake, serum triglycerides, total cholesterol, and high-density lipoproteins in an obese animal model.3 However, more research is required to prove such claims. Elliott HL, Macdougall AI: Aluminium studies in dialysis encephalopathy. The lifestyle section talks about food habits, home remedies, psychology, fitness and much more. -Antifungal13, The presence of potassium alum reduces swollen mucous membranes that result from inflammation of the nasal, gastrointestinal and urinary passages as well as in the presence of excessive secretions. /Aluminum/, Banks WA, Kastin AJ; Neurosci Biobehav Rev 13 (1): 47-5 (1989), InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4, [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]. 15th ed. 1978 Nov;92(5):712-20. Hematuria ceased in three patients followed up for 5 to 10 months. If phosphate intake is limited in patients with normal renal function, aluminum antacids (except aluminum phosphate) decrease phosphate absorption and hypophosphatemia and hypophosphaturia occur; calcium absorption is increased. InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4, [Al+3].[K+].[O-]S([O-])(=O)=O. Though there are studies that show the potential use of apricot in various conditions, but these are insufficient and there is a need of further studies to establish the true extent of benefits of apricot on human health. [K+], Alaun, Potash alum, Potassium aluminum sulfate, Alum potassium, Exsiccated alum, Burnt alum. Hoover, et al. The results of the study indicated potential in tumour growth reduction in the animal model.3 However, more research is required to prove such claims. Kindly consult a doctor before using it. In India, it is primarily found in Assam, Punjab, and Bihar.2. /Aluminum/, That the kidney is responsible for the elimination of a major portion of absorbed aluminum is reflected in the fact that, in dogs undergoing renal dialysis ligation of the ureter (resulting in cessation of urinary output) causes a greater increase in plasma aluminum concn than in intact dogs undergoing comparable dialysis. Remington's Pharmaceutical Sciences. Alum is used in depilatory waxes that are used for the removal of body hair or applied to freshly waxed skin as a demulcent (relieves inflammation or skin irritation).1 However, a doctor/specialist should be consulted before using it for the above-mentioned purpose. -Part of formulation in cleansing products, skin-care products, mosturizers, face powders and deodorants12 Alum, either as a solid or as a solution, may be used as a haemostatic for superficial abrasions and cuts and ulcers on the lips. /Aluminum potassium sulfate/, The Merck Index. Potassium alum does not go through a metabolic pathway. /ALUMINUM/, Friberg, L., Nordberg, G.F., Kessler, E. and Vouk, V.B. Kindly do not self-medicate as healing of post-operative wounds is crucial. As the molecular formula of alum contains water molecule, it is water-soluble.1,2, Yes, we can drink alum water as alum is used for water purification.1 There may be some reactions and side effects of alum, thus take advice from your doctor, Yes, alum is edible. McEvoy G., Miller J. and Litvak K. (1990). The high aluminum loading group received solutions with measured aluminum content of 306 + or - 16 ug/l and the low aluminum loading group received solutions with 144 + or - 16 ug aluminum/l. The antifungal activity of alum was tested on yeast isolated from mouth lesions. Available from: Zeenat F, Ahmad W, Mustafa S, Naaz SA, Ahmad A. For example, high intakes of aluminum decrease absorption of phosphorus (as phosphate) by forming insoluble aluminum phosphate and increasing the excretory loss of phosphorus. Such alterations in the access to the brain of nutrients, hormones, toxins, and drugs could be the basis of CNS dysfunction. Alum is a mineral found in nature in both pure and impure forms. Easily compare up to 40 drugs with our drug interaction checker. 21. Burdock G. (1997). This high affinity of aluminum for plasma proteins strongly suggests high levels of binding of aluminum to a variety of tissue proteins. 10th ed. Potassium alum may increase the hyperkalemic activities of Amlodipine. /Aluminum salts, from table/, Ellenhorn, M.J. and D.G. Under the doctor speak section, we have authentic articles by renowned doctors and medical experts from their field. Topical application of alum might be helpful for ulcers caused by recurrent usage of several medications like antibiotics, painkillers, etc.1 However, more research is required to prove such claims. Potassium alum is formed by large, transparent crystals that are used in different products like food or drugs as a buffer, neutralizing or forming agent.4. About 17-30% of the aluminum chloride formed is absorbed and is rapidly excreted by the kidneys in patients with normal renal functions. In addition to forming aluminum chloride, dihydroxyaluminum sodium carbonate and aluminum carbonate form carbon dioxide, and aluminum phosphate forms phosphoric acid. Also Read: Parijat: Uses, Benefits, Side effects and More! Handbook of the Toxicology of Metals. Effective Home Remedies For Vaginal Dryness, Simple Home Remedies For Skin Allergies and Rashes, It might have an antiplatelet (prevents platelet aggregation) property, It may be an anti- haemorrhagic (stops bleeding) agent, It may have an anti-inflammatory potential. Each was treated by continuous irrigation of the bladder with potassium alum. It comes in four different colours: white, green, yellow, and red. It was shown that the component of plasma protein that binds aluminum is saturable. There was also increased deposition of the metal in the kidney, muscle, bone, and the gray matter of the brain, but not in the liver or in the white matter of the brain. Build, train, & validate predictive machine-learning models with structured datasets.
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